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The Super-selective Intra-Arterial Chemotherapy (SSIAC) program was formed as a result of our aim to tend for our patients quality of life and treating their cases in an individualized basis by providing them with the best possible service and care.

We offer SSIAC as an alternative treatment for various types of malignancies, including pancreatic, lung, prostate, breast, and brain cancer.

Our services include standard and compassionate treatments that can improve a patient's survival, quality of life, reducing cancer symptoms, while minimizing drug side effects.

IDOI is considered a leader in brain tumor treatment, and is renowned for controlling the disease in over 60 patients with Diffuse Intrinsic Pontine Glioma (DIPG), with increased overall survival and quality of life.

IDOI’s drugs, delivery methods, and procedures have been granted approval in different countries around the world as an option for, among others, retinoblastoma, bone and liver cancers (see publications).

Chemotherapy is the use of drugs to treat and fight cancer, it was used for the first time in the 1950s. Its usefulness has allowed many people to have full lives. The chemotherapy drugs your doctor or nurse administers have been tested numerous times, and research has shown that they are effective in helping fight cancer cells.

According to the American Cancer Society, there are currently more than 100 chemotherapy drugs. Doctors select certain medications according to the type of cancer and the stage of the disease.

Chemotherapy may be used to keep cancer from spreading, suppress its growth, kill cancer cells that might have spread to other parts of the body, relieve symptoms like pain or blockages caused by cancerous tumors, and cure cancer.

There are also different methods of chemotherapy administration:

Intra-arterial or IA

In IA chemotherapy, the drug is delivered via a microcatheter advanced directly into the arteries that supplies blood to the tumor to treat a single area (such as the liver, an arm, or leg). This method helps limit the effect the drug has on other parts of the body and is called regional chemotherapy.

Intrathecal or IT

IT chemotherapy is administered through a needle into the spinal canal and goes into the fluid that surrounds the brain and spinal cord to reach cancer cells there. This fluid is called the cerebrospinal fluid or CSF. This is important because most chemotherapeutic drugs delivered by IV or orally are unable to reach the brain due to the blood-brain barrier.


Chemotherapy can also be delivered to the CSF through a surgically implanted long-term catheter and port that can be administered under the scalp. This port is called an Ommaya reservoir; a small drum-like device with a small tube attached to it. The tube goes into the CSF in a cavity of your brain and stays in place under your scalp while treatment is done.

Intravenous or IV

Chemotherapeutic drugs are delivered right into the bloodstream through a catheter inserted into a forearm's vein.
Chemotherapy pills, capsules or liquid are swallowed  – just like other medicines.


Chemotherapeutic drugs may be given through a catheter into an enclosed area of the body such as the abdomen (this is called intraperitoneal chemotherapy) or chest (called intrapleural chemotherapy).

Intramuscular or IM

The drug is administered through a needle into a muscle (as an injection or shot).


A needle is used to administered the drug right into a tumor. It’s only possible when the tumor can be safely reached with a needle.


The chemotherapy is administered right into the bladder through a soft catheter. It stays in for a few hours and is then drained out, and the catheter is removed.


The drug is administered right on an area of cancer on the skin as a cream, gel, or ointment.